they aren't toxic they contain urushiol which people who get contact dermatitis from poison or poison sumac are allergic. The lady wants flirt vast majority of it is found in the vine the skin doesn't have enough to cause an outbreak unless you are severely allergic or already sensitized (having a reaction) And you wont become allergic to something simply by holding it enough. People suddenly develop new allergies all the time but it doesn't come from prolonged contact otherwise we would be severely allergic to our clothes due to the detergents we use to clean them and the air because of all the crazy nasty chemicals in it and perfume/cologne and a billion other things that are bad for "us/toxic/can have an allergic reaction" that we have prolonged contact to every day.